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- July 31, 2010 |
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Welcome to the #1 online source of information for Diabetes Specialists! An international online community of more than 10,000 Diabetes Specialists.
CME on Diabetes is a website built to transmit top-level CME conferences given by international experts in endocrinology, insulin resistance, prediabetes, metabolic syndrome and type 2 diabetes. More than 2.6 million slides have been viewed since the website launch. Thank you for your continued support and commitment!
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"Diabetes and Metabolic Syndrome - An Asian Perspective"Prof. Juliana Chan (biography)
English - 2005-04-14 - 32 minutes
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Summary :
In this presentation Dr. Chan gives an Asian perspective on diabetes and the metabolic syndrome, focusing on studies from China.
About 60 million Chinese adults of age 35-74 years are estimated to have diabetes or impaired fasting glucose, and Dr. Chan shows data from the DECODA study on the prevalence of diagnosed and undiagnosed DM, and IFG/IGT in Chinese and Japanese men and...
Learning objectives :
After viewing this presentation the participant will be able to discuss studies from Asian (mainly Chinese) populations on the following:
- The prevalence of obesity, diabetes and metabolic syndrome
- The relationship between metabolic syndrome and CVD
- The effect of weight reduction on components of the metabolic syndrome
Bibliographic references :
Gu D, Reynolds K, Duan X, Xin X, Chen J, Wu X, Mo J, Whelton PK, He J; InterASIA Collaborative Group.Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterASIA).Diabetologia. 2003 Sep;46(9):1190-8. Epub 2003 Jul 15.
The DECODA Study Group Age- and Sex-Specific Prevalence of Diabetes and Impaired Glucose Regulation in 11 Asian Cohorts Diabetes Care 26:1770-1780, 2003
Chee-Eng Tan, Stefan Ma, Daniel Wai, Suok-Kai Chew, and E.-Shyong TaiCan We Apply the National Cholesterol Education Program Adult Treatment Panel Definition of the Metabolic Syndrome to Asians?Diabetes Care 27: 1182-1186.
Jung-Nan Wei; Fung-Chang Sung; Chau-Ching Lin; Ruey-Shiung Lin; Chuan-Chi Chiang; Lee-Ming ChuangNational Surveillance for Type 2 Diabetes Mellitus in Taiwanese Children JAMA, Sep 2003; 290: 1345 - 1350.
Peter C. Y. Tong; Zoe S. K. Lee; Man-Mei Sea; Chun-Chung Chow; Gary T. C. Ko; Wing-Bun Chan; Wing-Yee So; Ronald C. W. Ma; Risa Ozaki; Jean Woo; Clive S. Cockram; Juliana C. N. Chan The Effect of Orlistat-Induced Weight Loss, Without Concomitant Hypocaloric Diet, on Cardiovascular Risk Factors and Insulin Sensitivity in Young Obese Chinese Subjects With or Without Type 2 Diabetes Archives of Internal Medicine, Nov 2002; 162: 2428 - 2435.
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"Epidemiology of Prediabetes and Metabolic Syndrome in Indians"Dr. A. Ramachandran (biography)
English - 2005-04-14 - 25 minutes
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Summary :
Objective: To highlight high prevalence and the peculiarities of prediabetic conditions and the metabolic syndrome in India.
Method: Epidemiological data on the prevalence and risk associations of prediabetic conditions, and occurrence and peculiarities in metabolic syndrome are described.
Results: Both IFG (8.7%) and IGT (8.1%) show high prevalence in India with an...
Learning objectives :
After viewing this presentation, participants will be able to discuss:
• The prevalence of prediabetes in the Indian population based on IGT and IFG;
• The prevalence of the metabolic syndrome among the Indian population.
Bibliographic references :
Ramachandran A, Snehalatha C, Vijay V.Temporal changes in prevalence of type 2 diabetes and impaired glucose tolerance in urban southern India.Diabetes Res Clin Pract. 2002 Oct;58(1):55-60
Ramachandran A, Snehalatha C, Kapur A, Vijay V, Mohan V, Das AK, Rao PV, Yajnik CS, Prasanna Kumar KM, Nair JD; Diabetes Epidemiology Study Group in India (DESI).High prevalence of diabetes and impaired glucose tolerance in India: National Urban Diabetes Survey.Diabetologia. 2001 Sep;44(9):1094-101.
Ramachandran A, Snehalatha C, Baskar AD, Mary S, Kumar CK, Selvam S, Catherine S, Vijay V.Temporal changes in prevalence of diabetes and impaired glucose tolerance associated with lifestyle transition occurring in the rural population in India.Diabetologia. 2004 May;47(5):860-5. Epub 2004 Apr 28.
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"Diabetes: The Global Pandemic"Prof. Paul Zimmet (biography)
English - 2004-04-14 - 53 minutes
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Summary :
In this One on One presentation Prof. Zimmet answers the question posed by Dr. Lawrence Leiter: ''What does epidemiology teach us about the causes of the diabetes epidemic and, more importantly, its potential prevention and treatment?''
Prof. Zimmet discusses the burden of diabetes worldwide, and presents data from several epidemiological studies. These studies tell us how the...
Learning objectives :
After viewing this presentation the participant will be able to discuss:
- The prevalence of diabetes and IGT in various populations around the world
- Global projections for the diabetes and IGT epidemics
- Type 2 diabetes in children and adolescents
- Approaches to preventing type 2 diabetes
Bibliographic references :
Michael L Booth, Tien Chey, Melissa Wake, Kevin Norton, Kylie Hesketh, Jim Dollman and Ian Robertson. Change in the prevalence of overweight and obesity among young Australians, 1969–1997 American Journal of Clinical Nutrition 2003; 77(1): 29-36.
VJ Carey, EE Walters, GA Colditz, CG Solomon, WC Willett, BA Rosner, FE Speizer and JE Manson. Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses' Health Study American Journal of Epidemiology 1997;145(7):614-619
David W. Dunstan, PHD, Paul Z. Zimmet, MD, Timothy A. Welborn, PHD, Maximilian P. de Courten, MD, Adrian J. Cameron, MPH, Richard A. Sicree, MPH, Terry Dwyer, PHD, Stephen Colagiuri, MD, Damien Jolley, MSC, Matthew Knuiman, PHD, Robert Atkins, MD and Jonathan E. Shaw, MD On Behalf of the AusDiab Steering Committee. The Rising Prevalence of Diabetes and Impaired Glucose Tolerance The Australian Diabetes, Obesity and Lifestyle Study Diabetes Care 2002; 25:829-834.
Anthony JG Hanley, Stewart B Harris, Joel Gittelsohn, Thomas MS Wolever, Brit Saksvig and Bernard Zinman. Overweight among children and adolescents in a Native Canadian community: prevalence and associated factors American Journal of Clinical Nutrition 2000; 71(3):693-700.
SB Harris, J Gittelsohn, A Hanley, A Barnie, TM Wolever, J Gao, A Logan and B Zinman. The prevalence of NIDDM and associated risk factors in native Canadians Diabetes Care 1997; 20(2):185-187.
Bo Isomaa, MD, Peter Almgren, MSC, Tiinamaija Tuomi, MD, Björn Forsén, MD, Kaj Lahti, MD, Michael Nissén, MD, Marja-Riitta Taskinen, MD and Leif Groop, MD. Cardiovascular Morbidity and Mortality Associated With the Metabolic Syndrome Diabetes Care 2001; (24):683-689.
Kitagawa T, Owada M, Urakami T, Yamauchi K. Increased incidence of non-insulin dependent diabetes mellitus among Japanese schoolchildren correlates with an increased intake of animal protein and fat. Clin Pediatr (Phila). 1998 Feb;37(2):111-5.
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"Diabetes: The Magnitude of the problem and it's relationship to the Metabolic Syndrome"Prof. Bernard Zinman (biography)
English - 2003-06-16 - 14 minutes
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Summary :
The prevalence of diabetes is expected to increase by 76% by 2025, and this increase seems to be taking place not only in Europe and North America, but in developing countries as well. Driving this epidemic is another one - the obesity epidemic, and we know that larger and larger food portions have been contributing to this. Regarding pathophysiology, we know that beta cell failure leads to type...
Learning objectives :
The participant will be given a recap of the recent foci of research on the pathophysiology of type 2 diabetes, as well as an introduction to baseline findings from the ADOPT study addressing the prevalence of the metabolic syndrome in recently diagnosed type 2 diabetics:
- Beta cell failure leads to type 2 diabetes, but treatment of insulin resistance improves many of its associated factors such as hyperinsulinemia, ambulatory BP, dyslipidemia, visceral fat, microalbuminuria and hyperglycemia, with data still to come on whether CVD outcomes can also be changed.
- New research is giving us more and more information on the role of “adipokines” in contributing to insulin resistance.
- The ADOPT Study has so far revealed a > 80% prevalence of metabolic syndrome in recently-diagnosed type 2 diabetics, and points to NCEP criteria as being superior to WHO criteria in identifying affected patients.
Bibliographic references :
Viberti G, Kahn SE, Greene DA, Herman WH, Zinman B, Holman RR, Haffner SM, Levy D, Lachin JM, Berry RA, Heise MA, Jones NP, Freed MI. A diabetes outcome progression trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes. Diabetes Care. 2002 Oct;25(10):1737-43.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
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"DM and Cardiovascular Disease in Women"Dr. Gillian Booth (biography)
English - 2003-05-23 - 28 minutes
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Summary :
We are now all familiar with the increased risk of heart disease in patients with diabetes mellitus (Haffner et al.1998. NEJM 339: 229-34). What about gender differences within this population? The Nurses Health Study showed a marked increase in the risk for diabetic women with a history of CHD to have a fatal CHD event if they had diabetes for over 15 years (Hu et al. 2001. Arch Int Med 161:...
Learning objectives :
The participant will review a substantial body of data derived from the Ontario Diabetes Database (ODD) elucidating the following points:
- DM reduces the gender gap in CVD
- Relatively higher CVD procedure use in men than in women
- Both genders – earlier and greater risk of CVD
Bibliographic references :
Arch Intern Med 2001 Jul 23;161(14):1717-23
The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women: 20 years of follow-up.
Hu FB, Stampfer MJ, Solomon CG, Liu S, Willett WC, Speizer FE, Nathan DM, Manson JE.
http://archinte.ama-assn.org/cgi/content/abstract/161/14/1717
N Engl J Med 1998 Jul 23;339(4):229-34
Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction.
Haffner SM, Lehto S, Ronnemaa T, Pyorala K, Laakso M.
http://content.nejm.org/cgi/content/abstract/339/4/229
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"Microalbuminuria and Kidney Disease In Type 2 Diabetes"Dr. Steven Soroka (biography)
English - 2002-11-23 - 28 minutes
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Summary :
Here we will get a nephrology perspective on type 2 diabetes. Type 2 diabetes and chronic kidney disease are both common, but microalbuminuria (MAU) is more closely correlated with CVD than is kidney disease. Two important questions we have been asking ourselves are: What are the modifiable risk factors for kidney disease? And, What is the most cost effective way of treating kidney disease and...
Learning objectives :
The participant will get a nephrology perspective on the delay of onset and treatment of diabetic nephropathy:
- Diabetes and chronic kidney disease are common
- Early, aggressive treatment is needed
- Blood pressure control is essential and cost effective
- RAAS blockade confers additional cardio renal protection
Bibliographic references :
Deira J, Diaz H, Grande J. 2003. Complete blockade of the Renin-Angiotensin system in patients with advanced diabetic nephropathy. Diabetes Care 2003 May;26(5):1635-6
Jungmann E. 2003. Prevention and treatment of diabetic nephropathy in older patients. Drugs Aging 2003;20(6):419-35
http://www.ncbi.nlm.nih.gov/
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"Genetics, Environment and a Global Epidemic"Dr. Salim Yusuf (biography)
English - 2002-10-28 - 31 minutes
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Summary :
It is not commonly recognized that the majority of cardiovascular disease now occurs in developing countries. While cardiovascular disease rates had increased in western countries between 1950 and 1980, they have come down markedly (by as much as 50%) in many countries, including Canada and the US. By contrast the age-adjusted rates of cardiovascular disease is increasing in most of the...
Learning objectives :
The presentation will outline the rising burden of obesity and diabetes globally and discuss the proposed hypotheses for the dramatic rise in metabolic syndrome.
Bibliographic references :
Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization.
Yusuf S, Reddy S, Ounpuu S, Anand S.
Population Health Research Institute and Division of Cardiology, McMaster University, Hamilton, Ontario, Canada. yusufs@mcmaster.ca
This two-part article provides an overview of the global burden of atherothrombotic cardiovascular disease. Part I initially discusses the epidemiologic transition which has resulted in a decrease in deaths in childhood due to infections, with a concomitant increase in cardiovascular and other chronic diseases; and then provides estimates of the burden of cardiovascular (CV) diseases with specific focus on the developing countries. Next, we summarize key information on risk factors for cardiovascular disease (CVD) and indicate that their importance may have been underestimated. Then, we describe overarching factors influencing variations in CVD by ethnicity and region and the influence of urbanization. Part II of this article describes the burden of CV disease by specific region or ethnic group, the risk factors of importance, and possible strategies for prevention.
Circulation 2001 Nov 27;104(22):2746-53
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